A
new study confirms a substantially increased risk of thyroid cancer among
people exposed to radiation during childhood and adolescence after the
1986 Chernobyl nuclear accident.
A total of 13,127 of
the 32,385 individuals living in the most contaminated area of the Ukraine
during the nuclear plant meltdown and who were under 18 at the time were
screened between 1998 and 2000, Dr. Geoffrey R. Howe of Columbia University
in New York and colleagues report. They found that 45 cases of thyroid
cancer occurred compared with 11.2 cases that would have been expected
in the absence of radiation exposure. Plus, the higher the dosage of radioactive
iodine, the greater the thyroid cancer risk.
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A spike in thyroid cancer
cases had already been observed among Ukraine residents who were children
and adolescents when the Chernobyl accident occurred. However, the researchers
note, increased rates of screening for thyroid cancer and a low dietary
iodine intake, which increases the uptake of radioactive iodine by the
thyroid gland, "almost certainly" were factors in this increase.
To investigate the specific risk associated with radiation exposure, the researchers estimated each person's radiation exposure using measurements made after the accident and from interviews. They found a "strong" relationship between radiation exposure and thyroid cancer risk. While there was a tendency for risk to be greater among people exposed at younger ages, as well as among females, neither was statistically significant. "We estimate that 75% of the thyroid cancer cases would have been avoided in the absence of radiation," the researchers conclude. "This estimate demonstrates a substantial contribution of radioactive iodines to the excess of thyroid cancer that followed the Chernobyl accident." SOURCE: Journal of the National Cancer Institute, July 5, 2006. http://jncicancerspectrum.oxfordjournals.org/ |